Authors: Dr. T. Clarina and Dr. A. Muthuvinothini

ISBN: 978-81-984464-8-0

DOI: https://doi.org/10.59646/cm/308

Date of Publication: February 12, 2025

About the Book:

Chemistry plays a vital role in medicine, shaping the development, diagnosis, and treatment of various diseases. This book, “Chemistry in Medicine,” provides a fundamental understanding of the chemical principles involved in medical applications, first aid, disease management, clinical chemistry, and healthcare medicines. It aims to bridge the gap between chemistry and medicine, emphasizing the significance of chemical substances in human health. This book serves as a valuable resource for students, healthcare professionals, and anyone interested in the chemical aspects of medicine. By integrating fundamental chemical concepts with their medical applications, it enhances the knowledge required for effective healthcare practices. The content has been carefully compiled from numerous textbooks and reference materials, particularly Dr. Jayashree Ghosh’s        “A Textbook of Pharmaceutical Chemistry,” along with insights from various academic sources and online references.

We extend our sincere gratitude to our beloved professors of Department of Chemistry & Research Centre, Sarah Tucker College, Tirunelveli for their guidance and motivation. We are deeply grateful to our esteemed Chairman, Dr. J. Praveen Christopher as well as the management for their unwavering support and encouragement in bringing this book to life. We also acknowledge the efforts of San International Publications and their dedicated editorial team for their commitment to publishing this book with the highest standards.

Syllabus

Unit I: First Aid

First Aid for accidents – important rules – first aid kit, First aid for cuts, bruises, bleeding, fractures, burns, fainting and poisonous bites. Common poisons Acid poisoning – antidote, Alkali poisoning-antidote, Poisoning by disinfectant – symptoms antidote, Alkaloid poisoning – symptoms – antidote, alcohol poisoning – symptoms – antidote, Mercury poisoning – antidote and Salicylate poisoning – antidote.

Unit II: Chemicals in Medicine

(Preparations and chemical equations not required) Alum – properties and uses – Aluminium hydroxide gel – uses – Dried Aluminium hydroxide gel – uses – Aluminium acetate – uses – Ferrous fumarate uses Ferric ammonium citrate uses. Ferrous gluconate uses Ferrous sulphate. Biological importance of sodium, potassium, calcium, lodine and copper.

Unit III: Causes and Treatment of Some Common Diseases

Insect borne diseases – malaria and filariasis – Prevention and treatment. Air borne diseases – diphtheria, whooping cough, influenza, measles, mumps, common cold, tuberculosis and leprosy – Prevention and treatment. Water borne diseases – cholera, typhoid and diarrhoeal diseases Prevention and treatment. Respiratory disorder – Prevention and treatment of asthma. Nervous disorder – epilepsy – Prevention and treatment – other diseases – Peptic ulcer – treatment.

Unit IV: Clinical Chemistry

Clinical chemistry-Composition of blood – blood grouping – determination of blood groups and matching – blood pressure – hypertension – determination. Determination of glucose in serum – Folin and Wu’s method – determination of serum cholesterol – Sackett’s method – tests for cholesterol. Estimation of glucose in urine – Diagnostic test for sugar in urine Benedict’s test – Clinistix strip test Diagnostic test for salts in and serum. Detection of diabetes, detection of anaemia. Estimation of hemoglobin (Hb concentration) – estimation of red blood cells – Normal RBC count in adults.

Unit-V: Health Care Medicines

Vitamins – Classification of Vitamins – Sources – deficiency diseases of Vitamins A, D, E, K, B, B2, B3, B6, B₁₂ and C – Therapeutic uses. Treatment of ulcers and skin diseases.